hmmsearch - search a sequence database with a profile HMM
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 animalESC2_g.hmm [animalESC2]
Sequence database:        /nfs/scrap/common/proteome/Sp.fa
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: animalESC2||
  [HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence      Description                               Score    E-value  N 
--------      -----------                               -----    ------- ---
SPBC1921.02   |rad60||involved in DNA repair (PMID 11   -27.9    0.00073   1
SPBC365.06    |pmt3|ubl2, smt3|ubiquitin family prote   -61.4       0.31   1
SPBC713.02c   |ubp21|ubpD, ubp15|ubiquitin C-terminal   -69.1        1.3   1
SPCC553.08c   |||translation elongation factor (predi   -73.1        2.6   1
SPAC14C4.02c  |spr18|smc5|SMC family (PMID 10747036)|   -74.5        3.4   1
SPAC4H3.02c   |||sequence orphan|Schizosaccharomyces    -74.6        3.4   1
SPBC13E7.10c  |brf1|SPBC30D10.20|transcription factor   -75.2        3.8   1
SPCC550.14    |||RNA-binding protein|Schizosaccharomy   -76.1        4.5   1
SPAP7G5.04c   |lys1||aminoadipate-semialdehyde dehydr   -76.5        4.8   1
SPAC17A5.12   |ucp7||UBA domain|Schizosaccharomyces p   -77.0        5.2   1
SPBC16H5.08c  |||ATPase|Schizosaccharomyces pombe|chr   -79.6        8.4   1
	[no more scores below E threshold]

Parsed for domains:
Sequence      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
SPBC1921.02     1/1     226   405 ..     1   186 []   -27.9  0.00073
SPBC365.06      1/1       1   106 [.     1   186 []   -61.4     0.31
SPBC713.02c     1/1     828   999 ..     1   186 []   -69.1      1.3
SPCC553.08c     1/1     589   746 ..     1   186 []   -73.1      2.6
SPAC14C4.02c    1/1     761   909 ..     1   186 []   -74.5      3.4
SPAC4H3.02c     1/1     186   341 ..     1   186 []   -74.6      3.4
SPBC13E7.10c    1/1     265   407 ..     1   186 []   -75.2      3.8
SPCC550.14      1/1    1004  1164 ..     1   186 []   -76.1      4.5
SPAP7G5.04c     1/1     458   593 ..     1   186 []   -76.5      4.8
SPAC17A5.12     1/1      29   191 ..     1   186 []   -77.0      5.2
SPBC16H5.08c    1/1     140   292 ..     1   186 []   -79.6      8.4

Alignments of top-scoring domains:
SPBC1921.02: domain 1 of 1, from 226 to 405: score -27.9, E = 0.00073
                   *->eneeftvkvrIlDceseierlklRmsdilekFeevfkelAsklgvdp
                        ++  + +   D+e+ ++ +k+   +    F  v+  ++ +  vd 
  SPBC1921.0   226    RIPNSNISLP-RDWEAPLF-FKVKSNQ---QFRRVRIAYSERKKVD- 266  

                   scIlLllgdnevgpsdTPhslg.......lkpa.....dii.dgvvlask
                     ++L +  +++  + TP   g  + +++l+++   ++d+i++ ++    
  SPBC1921.0   267 -NVVLVFQNQRLWDYGTPKGAGmlkvdtrLVVHaychsDFIsLKRIKELE 315  

                   eekepaakissevetieeksdkisiKVQgkkrkkpLevsvkkdttlkvlm
                    ek+ +  ++s    +  + + i++  +  ++   L++s+  d t+k+l 
  SPBC1921.0   316 VEKLSSVTEDS----TAQTCKLITL-LLRSSKSEDLRLSIPVDFTVKDLI 360  

                   iKvaEalgldkeEnIPSlrkiklfFDGeklknnndtpedLdLEgdDiIev
                   +++  + + +        + i+l F+Ge l++n d      LE+ D   v
  SPBC1921.0   361 KRYCTEVKISFH------ERIRLEFEGEWLDPN-DQVQSTELEDEDQVSV 403  

                   wf<-*
                        
  SPBC1921.0   404 VL    405  

SPBC365.06: domain 1 of 1, from 1 to 106: score -61.4, E = 0.31
                   *->eneeftvkvrIlDceseierlklRmsdilekFeevfkelAsklgvdp
                       +e+    ++                d                 +d 
  SPBC365.06     1    MSESPSANIS----------------D-----------------ADK 14   

                   scIlLllgdnevgpsdTPhslglkpadiidgvvlaskeekepaakissev
                   s I+      + g                    ++s  +           
  SPBC365.06    15 SAIT-----PTTG--------------------DTSQQD----------- 28   

                   etieeksdkisiKVQgkkrkkpLevsvkkdttlkvlmiKvaEalgldkeE
                        + + i +KV g +    +   +kk+t ++ lm+ + +  g +   
  SPBC365.06    29 --VKPSTEHINLKVVGQD-NNEVFFKIKKTTEFSKLMKIYCARQGKSM-- 73   

                   nIPSlrkiklfFDGeklknnndtpedLdLEgdDiIevwf<-*
                         ++++  DGe++ +  +tp++Ld+E++D Ie      
  SPBC365.06    74 -----NSLRFLVDGERIRPD-QTPAELDMEDGDQIEAVL    106  

SPBC713.02c: domain 1 of 1, from 828 to 999: score -69.1, E = 1.3
                   *->eneeftvkvrIlDceseierlklRmsdilekFeevfkelAsklgvdp
                         +f+ + +  D   + ++l+l  +       + ++  A+kl+vdp
  SPBC713.02   828    ---TFEPRYS-DDTNNGVFDLVLTTHT---NYTDMARAVANKLNVDP 867  

                   scIlLllgdnevgpsdTPhslglkp..adiidgvvlaskeekepaakiss
                   +   + +      ps TP+s    p+++++    + + + ++++      
  SPBC713.02   868 NYLQFTMAHL---PSRTPRSVIRNPskFTLQNAIPSTYSHNQNVVMFYEV 914  

                   evetieeksdkisiKVQ....gkkrkkpLevsvkkdttlkvlmiKvaEal
                     +t+ e   k  i+V   ++g +     e  v+k+ t+++++ +v    
  SPBC713.02   915 LDITLSELERKQLIRVHflsnGISHETQMEFYVDKEGTVEDILRQVTQKV 964  

                   gldkeEnIPSlrkiklf.FDGeklknnndtpedLdLEgdDiIevwf<-*
                    l +e      + ++l++  ++++  +  +p d       i ++     
  SPBC713.02   965 PLNAE----DASRLRLYeVYNHRILKS-HLPTD------GIYDLNE    999  

SPCC553.08c: domain 1 of 1, from 589 to 746: score -73.1, E = 2.6
                   *->eneeftvkvrIlDceseierlklRmsdile.kFeevfkelAsklgvd
                      + +   ++v      +e +++  +    le+ +++++   A k  + 
  SPCC553.08   589    ADPCVQIAVE---ENGEHVIMCAGEIH-LErCLKDLRERFA-KIEIQ 630  

                   pscIlLllgdnevgpsdTPh........slglkpadiidg....vvlask
                    s+ l+ + ++++    TP+   ++++ s+g + a+++ g+ +  ++ ++
  SPCC553.08   631 ASQPLVPYRETTIA---TPDllaknkelSIGFVTATLPVGgvtiGITVTP 677  

                   eekepaakissevetieeksdkisiKVQgkkrkkpLevsvkkdttlkvlm
                     + +         tie++s  +s      k+   ++vs + +  +++  
  SPCC553.08   678 LSGSVVDFLLKHSKTIENVSSNFS------KKNRNVVVSESLTKSMEE-- 719  

                   iKvaEalgldkeEnIPSlrkiklfFDGeklknnndtpedLdLEgdDiIev
                          +l++e         k++   e+l+        L  E  D+ e+
  SPCC553.08   720 -------VLTPE---------KFY---ERLSKL------LEEENSDLGEL 744  

                   wf<-*
                   +    
  SPCC553.08   745 KN    746  

SPAC14C4.02c: domain 1 of 1, from 761 to 909: score -74.5, E = 3.4
                   *->eneeftvkvrIlDceseierlklRmsdilekFeevfkelAs.klgvd
                      +++ ++   +    e + +  + R  ++ + ++++ + lAs ++ + 
  SPAC14C4.0   761    AKYKLE---K---HEMDANQVNARLTEVQDRLKDITDKLASaREDA- 800  

                   pscIlLllgdnevgpsdTPhslglkpadiidgvvlaskeekepaakisse
                        ++l+++ v+   T +s   +  + +  ++ +s+e   + +kis e
  SPAC14C4.0   801 -----MSLYGSVVDSLQTQSSDRQTAITELNEEFATSSE---VDNKISIE 842  

                   vetieeksdkisiKVQgkkrkkpLevsvkkdttlkvlmiKvaEalgldke
                     ++   +    +  Q + rkk +e   +k + +   +   +++++  ke
  SPAC14C4.0   843 ETKLKFMNVNSYVMEQYDARKKEIEELESKMSDFDQSVEELQDEMNSIKE 892  

                   EnIPSlrkiklfFDGeklknnndtpedLdLEgdDiIevwf<-*
                           ++      kl+ n             +I  +f   
  SPAC14C4.0   893 ------DWVS------KLEEN-----------VQCISDRF    909  

SPAC4H3.02c: domain 1 of 1, from 186 to 341: score -74.6, E = 3.4
                   *->eneeftvkvrIlDceseierlklRmsdile.kFeevfkelAsklgvd
                      +++  +v   I D  + ++rlk+R  +  +++  ++ k  +  lg +
  SPAC4H3.02   186    ASPGEPVEPLITD--ASLQRLKSRANE--DpTIFNILKRISKGLGTP 228  

                   pscIlLllgdnevgpsdTPhslglkpadiidgvvlaskeekepaakisse
                   + c lL    ne+           +p +++++   + ++ k  +  i   
  SPAC4H3.02   229 EQCMLLH---NELI----------GPSTFPLPKRAKKPPRKRITLSINQ- 264  

                   vetieeksdki.siKVQgkkrkkpLevsv....kkdt....tlkvlmiKv
                        +k + ++s+    k+ + +  + ++ ++++dt+   + ++ +++v
  SPAC4H3.02   265 ----QDKDEFFdSLINNKKEVRRHFDIVMefsdAPDTkwifPRESVLSHV 310  

                   aEalgldkeEnIPSlrkiklfFDGeklknnndtpedLdLEgdDiIevwf<
                      ++ dk+     l+ ++l F  +   +          E+  +I+v+  
  SPAC4H3.02   311 ---FNTDKK----KLEALSLLF--HVYRPT---------EDRNVIDVKT  341  

                   -*
                     
  SPAC4H3.02     -    -    

SPBC13E7.10c: domain 1 of 1, from 265 to 407: score -75.2, E = 3.8
                   *->eneeftvkvrIlDceseierlklRmsdilekFeevfkelAsklgvdp
                      ++++ + k+      +++++   R               +   +   
  SPBC13E7.1   265    QKRLDEFKLT---ESGDLSIADFRNIW--------LEGQSDPPSFTK 300  

                   scIlLllgdnevgpsdTPhslglkpadiidgvvlaskeekepaakissev
                   ++ +  +g + v+       ++ +      +   ++  ++          
  SPBC13E7.1   301 NQKFQQYGAQKVS------NIDHT-QEYMSPIKRTPDFDG---------- 333  

                   etieeksdkisiKVQgkkrkkpLevsvkkdttlkvlmiKvaEalgldkeE
                      e ks+++s  V  ++   p+++ +++     ++ + v E l++d   
  SPBC13E7.1   334 --NEVKSEELSQTVKVESQETPVHLKADE----REIRKEVTETLKGDE-- 375  

                   nIPSlrkiklfFDGeklknnndtpedLdLEgdDiIevwf<-*
                       lrki+l       +    t ed d  +d+i ++     
  SPBC13E7.1   376 ----LRKISLQVNVKFSEEE-VTLEDVD--DDEIEDILL    407  

SPCC550.14: domain 1 of 1, from 1004 to 1164: score -76.1, E = 4.5
                   *->eneeftvkvrIlDceseierlklRmsdilekFeevfkelAsklgvdp
                       +ee +  v+    +++ e+        le  ee+ ++   k  v+ 
  SPCC550.14  1004    NSEEERNSVV---LRGDKEIVEALETRLLEIVEELKNQVEEKIEVPQ 1047 

                   scIlLllgdnevgpsdTPhslglkpadiid.gvvlaskeekepaakisse
                    cI    g  + g   T + +  k  + +  + vl + e    + ++s+ 
  SPCC550.14  1048 RCISSIIG--RMG--STRRDIERKTSTMLNiPNVLDPEETVTITIVGSP- 1092 

                   vetieeksdkisiKVQgkkrkkpLevsvkkdttlkvlmiKvaEalgldke
                    e  e   ++i+ KV +    +++ v+   dt  +++m+     ++    
  SPCC550.14  1093 -ENCEKAKEMIQEKV-ASQYTQMITVP---DTVYESIMKGIL--MKKLR- 1134 

                   EnIPSlrkiklfFDGeklknnndtpedLdLEgdDiIevwf<-*
                         +++k+f D   +k++   p +  LE+ +  +  f   
  SPCC550.14  1135 ------SDLKVFVDTPEIKPV--QPTEVVLEDHE--DGVF    1164 

SPAP7G5.04c: domain 1 of 1, from 458 to 593: score -76.5, E = 4.8
                   *->eneeftvkvrIlDceseierlklRmsdilekFeevfkelAsklgvdp
                      + +++  +      e+     k R+      ++  f+ +A   + ++
  SPAP7G5.04   458    STPTLSFTSG---SEGIPKGVKGRHFS----LAYYFDWMAQEFNLSE 497  

                   scIlLllgdnevgpsdTPhslglkpadiidgvvlaskeekepaakissev
                   s+ + +l +   +p            di ++++l  +             
  SPAP7G5.04   498 SDRFTMLSGIAHDPIQ---------RDIFTPLFLGASL------------ 526  

                   etieeksdkisiKVQgkkrkkpLevsvkkdttlkvlmiKvaEalgldkeE
                     i  + + i    Q++ +     v v+  t+    m +  +a + ++  
  SPAP7G5.04   527 --IVPTAEDIGTPGQLAQWANKYKVTVTHLTPA---MGQLLAAQADEP-- 569  

                   nIPSlrkiklfFDGeklknnndtpedLdLEgdDiIevwf<-*
                    IPSl+   +fF G+ l  +            D++ +     
  SPAP7G5.04   570 -IPSLHH--AFFVGDILTKR------------DCLRLQV    593  

SPAC17A5.12: domain 1 of 1, from 29 to 191: score -77.0, E = 5.2
                   *->eneeftvkvrIlDceseierlklRmsdilekFeevfkelAsklgvdp
                      ++++++  v       +   ++l  s + ++F+++f+          
  SPAC17A5.1    29    PSYSLPAPVA----QKKNAQIPLKASKPEDPFANLFQK------KTD 65   

                   scIlL.llgdnevgpsd...TPhslglkpa...diidgvvlaskeekepa
                   + I L+ l  + vg+ d+++TP s ++ p+++  i++ +  +++      
  SPAC17A5.1    66 NKISLkELERQKVGTPDsnsTPKSSNYDPFenlEILHQLSNTPRDKD--- 112  

                   akissevetieeksdkisiKVQgkkrkkpLevsvkkdttlkvlmiKvaEa
                   a+i     +iee+   is         +p +vs+++  tlk+l       
  SPAC17A5.1   113 AVIHD---KIEENKRPIS---------QP-QVSASEKVTLKDLSLEPHQP 149  

                   lgldkeEnIPSlrkiklfFDGe.klknnndtpedLdLEgdDiIevwf<-*
                     l + EnI   +  +  F++++ + n  +t++d  L +++  e +    
  SPAC17A5.1   150 VSLPAFENIG--SETSIPFENHnEITNM-NTAKDK-LSSNEMYE-KL    191  

SPBC16H5.08c: domain 1 of 1, from 140 to 292: score -79.6, E = 8.4
                   *->eneeftvkvrIlDceseierlklRmsdilekFeevfkelAsklgvdp
                      e+e   v  +       i        +   k+e    el++   vd 
  SPBC16H5.0   140    EAEPSDVNAV-----DYIIQSAKDKVQ---KLEAEIEELSTADDVD- 177  

                   scIlLllgdnevgpsdTPhslglkpadiidgvvlaskeekepaakissev
                    ++lL   ++e++ +  P++   k a i++g+  +      p+   s   
  SPBC16H5.0   178 -DVLLESKYEELD-DMDPSTFEAKAAMILHGLGFTQEMMAKPTKDMSGGW 225  

                   etieeksdkisiK...VQgkkrkkpLevsvkkdttlkvlmiKvaEalgld
                         s ++ iK++  ++++   +L +++  +  l+  + K+   l+ +
  SPBC16H5.0   226 RMRVALSRALFIKpslLLLDEPTNHLDLEA--VVWLENYLAKYDKILVVT 273  

                   keEnIPSlrkiklfFDGeklknnndtpedLdLEgdDiIevwf<-*
                           ++       + l n+          +  iI++     
  SPBC16H5.0   274 S-------HS------QDFLNNV----------CTNIIDLTS    292  


Histogram of all scores:
score    obs    exp  (one = represents 4 sequences)
-----    ---    ---
<-203      6      -|==                                                         
 -203      0      0|                                                           
 -202      1      0|=                                                          
 -201      0      0|                                                           
 -200      2      0|=                                                          
 -199      0      0|                                                           
 -198      1      0|=                                                          
 -197      1      0|=                                                          
 -196      2      0|=                                                          
 -195      0      0|                                                           
 -194      1      0|=                                                          
 -193      1      0|=                                                          
 -192      0      0|                                                           
 -191      2      0|=                                                          
 -190      0      0|                                                           
 -189      3      0|=                                                          
 -188      1      0|=                                                          
 -187      0      0|                                                           
 -186      0      0|                                                           
 -185      1      0|=                                                          
 -184      1      0|=                                                          
 -183      2      0|=                                                          
 -182      0      0|                                                           
 -181      6      0|==                                                         
 -180      2      0|=                                                          
 -179      1      0|=                                                          
 -178      2      0|=                                                          
 -177      2      0|=                                                          
 -176      1      0|=                                                          
 -175      0      0|                                                           
 -174      1      0|=                                                          
 -173      5      0|==                                                         
 -172      2      0|=                                                          
 -171      3      0|=                                                          
 -170      0      0|                                                           
 -169      4      0|=                                                          
 -168      3      0|=                                                          
 -167      5      0|==                                                         
 -166      5      0|==                                                         
 -165      6      0|==                                                         
 -164      7      0|==                                                         
 -163      4      0|=                                                          
 -162      4      0|=                                                          
 -161      4      0|=                                                          
 -160      9      0|===                                                        
 -159      8      0|==                                                         
 -158      8      0|==                                                         
 -157      8      0|==                                                         
 -156      6      0|==                                                         
 -155      6      0|==                                                         
 -154     10      0|===                                                        
 -153     16      0|====                                                       
 -152     17      0|=====                                                      
 -151     19      0|=====                                                      
 -150     13      0|====                                                       
 -149     18      0|=====                                                      
 -148     18      0|=====                                                      
 -147     12      0|===                                                        
 -146     20      0|=====                                                      
 -145     16      0|====                                                       
 -144     22      0|======                                                     
 -143     23      0|======                                                     
 -142     18      0|=====                                                      
 -141     16      0|====                                                       
 -140     25      0|=======                                                    
 -139     36      0|=========                                                  
 -138     23      0|======                                                     
 -137     32      0|========                                                   
 -136     46      0|============                                               
 -135     29      0|========                                                   
 -134     54      0|==============                                             
 -133     46      0|============                                               
 -132     49      0|=============                                              
 -131     44      0|===========                                                
 -130     65      0|=================                                          
 -129     61      0|================                                           
 -128     74      0|===================                                        
 -127     81      2|*====================                                      
 -126     90      7|=*=====================                                    
 -125     85     18|====*=================                                     
 -124    100     38|=========*===============                                  
 -123    109     69|=================*==========                               
 -122    112    110|===========================*                               
 -121    127    158|================================       *                   
 -120    116    208|=============================                      *       
 -119    129    254|=================================                         *
 -118    133    291|==================================                        *
 -117    152    317|======================================                    *
 -116    152    329|======================================                    *
 -115    169    331|===========================================               *
 -114    160    322|========================================                  *
 -113    166    305|==========================================                *
 -112    178    284|=============================================             *
 -111    187    259|===============================================           *
 -110    181    233|==============================================            *
 -109    174    207|============================================       *       
 -108    149    182|======================================       *             
 -107    134    158|==================================     *                   
 -106    130    137|================================= *                        
 -105    137    118|=============================*=====                        
 -104    105    101|=========================*=                                
 -103    108     86|=====================*=====                                
 -102     86     73|==================*===                                     
 -101     90     62|===============*=======                                    
 -100     71     52|============*=====                                         
  -99     76     44|==========*========                                        
  -98     41     37|=========*=                                                
  -97     47     31|=======*====                                               
  -96     41     26|======*====                                                
  -95     26     22|=====*=                                                    
  -94     31     18|====*===                                                   
  -93     25     15|===*===                                                    
  -92     24     12|==*===                                                     
  -91     18     10|==*==                                                      
  -90     31      9|==*=====                                                   
  -89     13      7|=*==                                                       
  -88      9      6|=*=                                                        
  -87     10      5|=*=                                                        
  -86      7      4|*=                                                         
  -85      9      3|*==                                                        
  -84      2      3|*                                                          
  -83      2      2|*                                                          
  -82      3      2|*                                                          
  -81      1      1|*                                                          
  -80      1      1|*                                                          
  -79      0      1|*                                                          
  -78      0      1|*                                                          
  -77      3      0|=                                                          
  -76      1      0|=                                                          
  -75      2      0|=                                                          
> -74      4      -|=                                                          


% Statistical details of theoretical EVD fit:
              mu =  -114.9050
          lambda =     0.1809
chi-sq statistic =  2186.8040
  P(chi-square)  =          0

Total sequences searched: 4997

Whole sequence top hits:
tophits_s report:
     Total hits:           96
     Satisfying E cutoff:  11
     Total memory:         23K

Domain top hits:
tophits_s report:
     Total hits:           96
     Satisfying E cutoff:  96
     Total memory:         87K
